The Substance

Demi Moore

Elisabeth

Margaret Qualley

Sue

Dennis Quaid

Harvey

Edward Hamilton-Clark

Fred

Gore Abrams

Oliver

Oscar Lesage

Troy

Christian Erickson

Man at Diner

Robin Greer

Male Nurse

Tom Morton

Doctor

Hugo Diego Garcia

Diego - Boyfriend

Daniel Knight

Casting Director

Jonathon Carley

Assistant Casting Director

Jiselle Henderkott

Girl Auditioning / New Year's Eve Show Dancer

Akil Wingate

TV Host

Vincent Colombe

Man in Suit #1 - Harvey's Office